This guide explains how effective measurement and evaluation of self-management support can provide insight into potential improvements.This can be done at the individual level, service and organizational level, and commissioning and planning level. The authors consider strategies to enable those with long-term health conditions to interact effectively with health care providers and gain greater autonomy and confidence in managing their symptoms. They note that measurements from different levels can be combined to provide a complete picture of the effectiveness of self-management support. They also comment on emerging resources that can help to measure the issues of greatest concern to patients and carers.