Some copies of the Gutenberg Bible have very extensive manuscript notes. They help to understand how these copies were used. Some of them state that they were used for reading out in a refectory, for monks during their meals.
The British Library's copies do not give us such clear information,
but in some passages there are marks to assist with the pronunciation
of the Latin, indicating that the copy of the Bible was in part intended
to be used for reading aloud. There are also a few corrections to
the text.
The best discussion of marks of use in the Gutenberg Bible is Gerhardt
Powitz, Die Frankfurter Gutenberg-Bibel: Ein Beitrag zum Buchwesen
des 15. Jahrhunderts (Frankfurt am Main: Klostermann, 1990). ISBN
3465022319.